Recently, expression of the γ2 chain of laminin-5, an epithelial cell–specific laminin, was predominantly detected at the invasive front of cancer cells of the colon, pancreas, stomach and oesophagus (Pyke et al, 1995; Soini et al, 1996; Sordat et al, 1998; Koshikawa et al, 1999; Yamamoto et al, 2001). Here, LAMB2 is linked to cancer.