On the other hand, the expression of Waf-1 did not relate to that of p53 in these tumours (Table 5) which might not be unexpected, as Waf-1 expression is not exclusively controlled by p53 (Halevy et al, 1995; Russo et al, 1995; Liu et al, 1996). The gene discussed is CDKN1A; the disease is neoplasm.