This result is comparable to the results from a study (Maris et al, 2000) in which LOH at 1p36 predicted progression free survival, but not decreased overall survival in patients with single copy of MYCN. Tumour suppressor genes responsible for the development of neuroblastoma are assumed to be present on chromosome 1p36, but no conclusive results on the identification and location of such genes for LOH analysis have yet been reported. This evidence concerns the gene MYCN and neoplasm.