Furthermore, re-expression of caveolin-1 inhibited the growth of breast carcinoma cells (Lee et al, 1998) and colony formation of sarcoma cells (Razani et al, 2000) and ectopic caveolin-1 expression reduced tumorigenecity of colon carcinoma cells (Bender et al, 2000). The gene discussed is CAV1; the disease is colon carcinoma.