Thus far, a decreased expression of caveolin-1 has been found in a variety of cell lines such as those of breast carcinoma (Lee et al, 1998), lung carcinoma (Racine et al, 1999), sarcoma (Wiechen et al, 2001), uterine cervical carcinoma (Razani et al, 2000), and colon carcinoma (Bender et al, 2000). This evidence concerns the gene CAV1 and sarcoma.