Since the values of serum VEGF in drawn blood samples can be increased during clot formation (Banks et al, 1998; Webb et al, 1998; Salven et al, 1999; George et al, 2000; Lee et al, 2000), it is possible that increased serum VEGF levels seen in the present study may not be a true reflection of tumour angiogenic activity. Here, VEGFA is linked to neoplasm.