Furthermore, in subsequent reports, BAI1 has been found to be absent or significantly reduced in glioblastomas (Nishimori et al, 1997), but also in many colorectal (Fukushima et al, 1998; Yoshida et al, 1999), breast cancers (Nishizaki et al, 1999), and lung cancers (Hatanaka et al, 2000), as compared to the extraneoplastic tissues. The gene discussed is ADGRB1; the disease is glioblastoma.