EGFR and ovarian cancer: We have previously demonstrated that one of these inhibitors, ZM 252868 (PD 153035, 4(3-bromoanilino)-6,7-dimethoxyquinazoline) inhibited ovarian cancer cell growth and tyrosine phosphorylation on the EGFR (Simpson et al, 1999), however this compound was ineffective in vivo (Kunkel et al, 1995).