Ovarian cancers that express increased concentrations of the EGF receptor are associated with poor survival (Berchuck et al, 1991; Bartlett et al, 1996) and both TGFα and EGF have been shown to stimulate growth of ovarian cancer cells in culture (Morishige et al, 1991; Crew et al, 1992). This evidence concerns the gene TGFA and ovarian cancer.