VEGFA and colorectal carcinoma: Furthermore, the analysis showed that the patients with the highest 10% of the serum VEGF concentrations had a significantly (P=0.0005) reduced survival compared to the CRC patients with lower VEGF concentrations, while the patients with the lowest 10% of the serum VEGF concentrations had a significantly (P=0.04) better prognosis than the patients with higher preoperative serum VEGF concentrations.