However, in the present experiments, the proportions of specimens exhibiting positive staining of the epithelial cells for S100A4 were somewhat different from those in the previous study, 33% of adenomas positive (0% positive, previously), 38% of adenocarcinoma specimens positive (94% positive, previously), 71% of liver metastases positive (100% positive, previously). This evidence concerns the gene S100A4 and adenocarcinoma.