Many studies have investigated the expression patterns of Ang1, other angiopoietins, and Tie2 in a variety of tumours, including cancers of the breast (Hayes et al, 2000; Currie et al, 2001), brain (Stratmann et al, 1998; Zagzag et al, 1999; Eggert et al, 2000), liver (Tanaka et al, 1999), ovary (Martoglio et al, 2000), lung (Takahama et al, 1999; Wong et al, 2000), Kaposi's sarcoma and cutaneous angiosarcoma (Brown et al, 2000), thyroid gland (Bunone et al, 1999), and leukaemia (Kukk et al, 1997). Here, ANGPT1 is linked to breast carcinoma.