Among the 10 patients in whom both the primary breast tumour and matched normal breast tissue were investigated, CCND1 expression was far higher in three tumours than in the normal tissue (NCCND1=8.1, 4.8 and 3.6, compared to 0.9, 1.2 and 0.2, respectively). The gene discussed is CCND1; the disease is breast neoplasm.