In the case of HCC, the positive rate was 46–80% of MAGE-1 transcript and 42–68% of MAGE-3 transcript in HCC tissue samples (Cai et al, 1999, 2000; Chen et al, 1999; Tahara et al, 1999; Yamashita et al, 1996). This evidence concerns the gene MAGEA3 and hepatocellular carcinoma.