TP53 and non-Hodgkin lymphoma: p53 is a tumor-suppressor gene whose disruption or loss is implicated in development or progression of several types of human cancer.1-3 Its inactivation is mainly caused by point mutations in the coding sequence of exons 5 to 9 in one allele, with or without loss of the other allele.4 Burkitt's lymphoma is a subgroup of nonHodgkin's lymphoma (NHL) with distinct epidemiological, clinical-pathological, immunological, and molecular features.