The gestational puerperal cycle is a transitory thrombotic state that may predispose to thromboembolic phenomena, whose major complication is the pulmonary thromboembolism, which may be fatal.14 Patients with thrombosis associated with a family history of this should be investigated (ATIII dosage, Leiden factor V, proteins C and S, homocysteine, AFA) and alerted to the risk of developing thromboembolic phenomena (Table) in the face of puerperium risk factors for nephrotic syndrome, surgeries, and immobilization.14 The gene discussed is SERPINC1; the disease is Venous thrombosis.