VIM and cystadenoma: It is possible that several of the reported cases of struma associated with cystadenoma represented an exclusively thyroid-type cyst.2 Follicular epithelia of both normal and goitrous thyroids have been shown to react with anti-VIM in only a few cells.3 In case 2, the epithelial lining was extensively missing, the cystic wall heavily calcified, and typical thyroid follicles could be found in different areas of its wall.