Chromosomal aberrations and SCE in lymphocytes of children revaccinated against smallpox.

Kucerová M; Polívková Z; Matousek V

doi:10.1016/0027-5107(80)90078-0

Abstract

Chromosomal changes were analysed in the peripheral lymphocytes of 14 twelve-year-old children before and 3 months and 10 months after smallpox revaccination (group A), and in peripheral lymphocytes of 8 children of the same age before and 1.5 and 8 months after revaccination (group B). A significantly increased number of aberrant cells was found after 1.5 and 3 months. In the blood samples collected 8 and 10 months after revaccination there was a decrease in the number of aberrant cells which, however, did not reach the control level. Sister chromatid exchanges (SCE) were counted in 5 children 1.5 and 8 months after revaccination, and their numbers did not differ from controls.

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References

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Chromosomal aberrations and SCE in lymphocytes of children revaccinated against smallpox.

Abstract

Full text links

References

Chromosome breaks in leukocytes of chickenpox patients

Cytogenetic investigation of peripheral blood lymphocytes in children re-immunized with smallpox vaccine

Chromosome studies in some virus infections.

Études cytogénétiques “in vivo” et “in vitro” après infections virales et après vaccination anti-amarile

Cytogenetic studies on patients with virus infections and subjects vaccinated against yellow fever

Leukocytes cultured from small inocula of whole blood and the preparation of metaphase chromosomes by treatment with hypotonic KCl.

CHROMOSOME ABERRATIONS IN LEUCOCYTES OF PATIENTS WITH ASEPTIC MENINGITIS.

Title not supplied

Chromosome after smallpox vaccination.

Measles associated chromosome breakage

Citations & impact

Impact metrics

Citations of article over time

Alternative metrics

Article citations

In vitro approaches to develop weight of evidence (WoE) and mode of action (MoA) discussions with positive in vitro genotoxicity results.

The risks of handling cytotoxic drugs. I. Methods of testing exposure.

Factors that influence formation of sister chromatid exchanges in human blood lymphocytes.

The need for characterization of pathogenicity genes of recombinant DNA viruses used as human vaccines.

Urine mutagenicity, chromosomal abnormalities and sister chromatid exchanges in lymphocytes of nurses handling cytostatic drugs.

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