In vitro Antibacterial Activity of Cyadox on Poultry Bacteria

The in vitro antibacterial activity of cyadox on 6 species 13 strains of clinical pathogenic bacteria in poultry was tested by microdilution method.The results showed that cyadox was active both on grampositiv bacteria and gramnegative bacteria, and more active on Escherichia coli, Staphylococcus aureus and Salmonellaspp. than the others. The MIC of these was 0.62, 1.25 and 0.62 μg/mL respectively. It showed germicidal action only on Escherichia coli, the MBC≥80#mu#g/mL. The antibacterial activity of cyadox was similar to that of olaquindox, stronger than that of sulfadimidine, and weaker than that of aureomycin. These results indicated that cyadox had strong bacteriostatic activity, and could be used as a drug additive to protect poultry from bacterial infection in the field.